Inter-test reproducibility of the lung clearance index measured by multiple breath washout
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چکیده
منابع مشابه
Slow and fast lung compartments in cystic fibrosis measured by nitrogen multiple-breath washout.
Imaging studies describe significant ventilation defects across a wide range of cystic fibrosis (CF) related lung disease severity. These are unfortunately poorly reflected by phase III slope analysis-derived Scond and Sacin from multiple-breath washout (MBW). Methodology extending previous two-lung compartment model-based analysis is presented describing size and function of fast- and slow-ven...
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BACKGROUND Accurate estimates of multiple breath washout (MBW) outcomes require correct operation of the device, appropriate distraction of the subject to ensure they breathe in a manner representative of their relaxed tidal breathing pattern, and appropriate interpretation of the acquired data. Based on available recommendations for an acceptable MBW test, we aimed to develop a protocol to sys...
متن کاملEquipment for multiple breath washout.
5 Demeo DL, Campbell EJ, Barker AF, et al. IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. We read with interest the article ''Paediatrics in Berlin'' [1] in a recent issue of the European Respiratory Journal, which sum-marised the paediatric topics of the European Respiratory Society's Annual Congress in Berlin. In this article, inert gas mul...
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Regular spirometry measurement is an accepted component of clinical monitoring of adults and school-age children with cystic fibrosis (CF). Specifically, the forced expired volume in 1 s (FEV1), or its rate of decline, is commonly used to monitor disease progression in individuals, and as an outcome measure in clinical trials. However, as the survival of subjects with CF improves, there has bee...
متن کاملThe influence of sighing respirations on infant lung function measured using multiple breath washout gas mixing techniques
There is substantial interest in studying lung function in infants, to better understand the early life origins of chronic lung diseases such as asthma. Multiple breath washout (MBW) is a technique for measuring lung function that has been adapted for use in infants. Respiratory sighs occur frequently in young infants during natural sleep, and in accordance with current MBW guidelines, result i...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2017
ISSN: 0903-1936,1399-3003
DOI: 10.1183/13993003.00433-2017